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David Mangelsdorf and Steven Kliewer
Dr. David Mangelsdorf
and Dr. Steven Kliewer

MedicalScience UT Southwestern Scientists Discover New Clues to How Weight Loss is Regulated

Dr. David Mangelsdorf, TAMEST Member and recipient of the 2007 O’Donnell Award in Medicine, and Dr. Steven Kliewer recently discovered that a hormone seen as a popular target to develop weight-loss drugs works by directly targeting the brain and triggering previously unknown activity in the nervous system. Read more about the research findings surrounding the FGF21 hormone and its role in weight loss…

Mouse Heart with Cardiac Micro Lesion
Mouse Heart with Cardiac

Medical Pneumonia Bacterium Leaves Tiny Lesions in the Heart, Study Finds

The long-observed association between pneumonia and heart failure now has more physical evidence, thanks to researchers in the School of Medicine at The University of Texas Health Science Center at San Antonio. The researchers found proof that Streptococcus pneumonia, the leading cause of community-acquired pneumonia, actually physically damages the heart. Read more about the lesion-causing bacterium and the candidate vaccine that can protect against it…

UT wordmark

ScienceChanges in Coastal Upwelling Linked to Variability in Marine Ecosystem off California

A new study links short-term reductions in growth and reproduction of marine animals off the California coast to increasing variability in the strength of coastal upwelling currents—currents that supply nutrients to the region’s diverse ecosystem. The University of Texas at Austin’s Marine Science Institute recently released these findings of relevance to conservationists and the fishing industry. Read more to find out about the extremely weak upwelling affecting California’s coast…


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